Botanical species · safety record

Xanthorhiza simplicissima

The EFSA Compendium of Botanicals holds 6 constituent measurements for Xanthorhiza simplicissima. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Xanthorhiza simplicissima Marshall

6Constituent measurements

0Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Live plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Berberine	Bark	Solvent extraction	177 Microgram/gram	HPLC-DAD	Resolve DOI
Bisbenzylisoquinoline alkaloids	Roots and other underground parts used as staple food	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Oxyacanthine	Roots and other underground parts used as staple food	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Liriodenine	Unspecified	Solvent extraction	—	—	No resolvable identifier
Palmatine	Unspecified	Solvent extraction	—	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Wu, Y C., Yamagishi, T., Lee, K H. Cytotoxic isoquinoline alkaloids from Xanthorhiza simplicissima.. Gaoxiong yi xue ke xue za zhi = the kaohsiung journal of medical sciences, 1989, vol. 5, no. 7, p. 409-11.
KNAPP, JE., HUSSEIN, FT., BEAL, JL., DOSKOTCH, RW., TOMIMATSU, T. ISOLATION OF 2 BISBENZYLISOQUINOLINE ALKALOIDS FROM RHIZOMES AND ROOTS OF XANTHORHIZA SIMPLICISSIMA . Journal of pharmaceutical sciences, 1967, vol. 56, no. 1, p. 139-+. DOI
OKUNADE, AL., HUFFORD, CD., RICHARDSON, MD., PETERSON, JR., CLARK, AM. ANTIMICROBIAL PROPERTIES OF ALKALOIDS FROM XANTHORHIZA-SIMPLICISSIMA. Journal of pharmaceutical sciences, 1994, vol. 83, no. 3, p. 404-406. DOI
Uzas�i, S., Erim, F.B. Enhancement of native fluorescence intensity of berberine by (2-hydroxypropyl)-beta-cyclodextrin in capillary electrophoresis coupled by laser-induced fluorescence detection: Application to quality control of medicinal plants. Journal of chromatography a, 2014, vol. 1338, p. 184-187. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature