Botanical species · safety record

Zanthoxylum clava-herculis

The EFSA Compendium of Botanicals holds 10 constituent measurements for Zanthoxylum clava-herculis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Zanthoxylum clava-herculis L.

10Constituent measurements

0Safety records

6Cited sources

27Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 27 licensed products naming Zanthoxylum clava-herculis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Bark
Stem bark

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Aporphine alkaloids	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Chelerythrine	Bark	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Lignans	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Magnoflorine	Unspecified	—	—	Unspecified	Resolve DOI
1,8-cineole	Leaves	Essential oil	≥ 12.9 Percent	GC-MS	No resolvable identifier
1,8-cineole	Leaves	Essential oil	≤ 43.3 Percent	GC-MS	No resolvable identifier
Alkaloids	Bark	—	—	Unspecified	No resolvable identifier
Benzophenanthridine alkaloids	Bark	—	—	—	No resolvable identifier
Isoquinoline alkaloids	Bark	—	—	—	No resolvable identifier
Myrcene	Bark	Essential oil	1.5 Percent	GC-MS	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Fish, F., Waterman, P. G. Alkaloids in the bark of Zanthoxylum clava-herculis. Journal of pharmacy and pharmacology, 1973, vol. 25(Suppl.), p. 115P-116P.
Gibbons, S., Leimkugel, J., Oluwatuyi, M., Heinrich, M. Activity of Zanthoxylum clava-herculis extracts against multi-drug resistant methicillin-resistant Staphylococcus aureus (mdr-MRSA) . Phytotherapy research, 2003, vol. 17, no. 3, p. 274-275. DOI
Steinberg, Kelly Marie., Satyal, Prabodh., Setzer, William N. Bark Essential Oils of Zanthoxylum clava-herculis and Ptelea trifoliata: Enantiomeric Distribution of Monoterpenoids . Natural product communications, 2017, vol. 12, no. 6, p. 961-963.
Eiter, Lauren C., Fadamiro, Henry., Setzer, William N. Seasonal Variation in the Leaf Essential Oil Composition of Zanthoxylum clava-herculis growing in Huntsville, Alabama . Natural product communications, 2010, vol. 5, no. 3, p. 457-460.
RAO, KV., DAVIES, R. THE ICHTHYOTOXIC PRINCIPLES OF ZANTHOXYLUM-CLAVA-HERCULIS. Journal of natural products, 1986, vol. 49, no. 2, p. 340-342. DOI
Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (E)-Herclavine (HMDB30242). Human metabolome database, 2012.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature